Patent ductus arteriosus stenting as a first stage method of the surgical treatment of tetralogy of Fallot with non-confluent branches of the pulmonary artery
Main Article Content
Abstract
The aim – to show the results of patent ductus arteriosus (PDA) stenting as the first stage of palliative treatment in patients with tetralogy of Fallot with non-confluent branches of the pulmonary artery.
Materials and methods. This retrospective, single-center study included 10 consecutive patients who underwent PDA stenting since 2013 to 2023. The average age at the time of surgery was 96.00 ± 82.92 days (range 4 to 411 days), the average weight was 5.10 ± 1.78 kg (range 2.8 to 11 kg). The arterial oxygen saturation level (SaO2) before the intervention was 72.0 ± 6.7 % (range 60 to 87 %).
Results. There were no intraoperative complications in all patients of this group. The length of the stay in the intensive care unit after surgery was 5.00 ± 1.36 days. SaO2 level increased to 89.00 ± 4.08 %. The duration of artificial lung ventilation after surgery was 36.5 ± 18.00 hours, and the duration of inotropic support was 81.1 ± 33.8 hours. In the long term, all patients showed significant growth of the native pulmonary artery branches. All patients of this group achieved total repair of this pathology after 192.00 ± 60.28 days, on average. At the moment of total repair, the size of the left branch of the pulmonary artery increased from 3.9 ± 0.8 mm to 7.8 ± 1.6 mm, and the right branch increased from 5.8 ± 1.2 mm to 7.70 ± 1.04 mm; the Nakata index increased from 133.0 ± 29.1 mm2/m2 to 241.2 ± 97.8 mm2/m2; end-diastolic index of the left ventricle increased from 31.4 ± 10.8 ml/m2 to 43.1 ± 11.4 ml/m2.
Conclusion. PDA stenting in patients with tetralogy of Fallot combined with non-confluent branches of the pulmonary artery is an effective palliative procedure. This method allows to postpone the total repair to an older age, ensures sufficient and symmetric growth of the branches of pulmonary artery, and helps to avoid risks associated with repeat open heart surgeries.
Article Details
Keywords:
References
Diaz-Frias J, Guillaume M. Tetralogy of Fallot. Brooklyn: StatPearls Publishin, 2022.
Swaminathan S, Agarwal A, Infante JC, Rosenkranz E. Tetralogy of Fallot with absent pulmonary valve and nonconfluent pulmonary arteries: a management conundrum. World Journal for Pediatric and Congenital Heart Surgery. 2020;11(4):168-71. https://doi.org/10.1177/2150135118775661.
Edraki M, Ghasemzadeh B, Keshavarz K, Amirghofran A, Mohammadi H, Kheirandish Z, Amoozgar H, Nirooei E, Ajami G, Mehdizadegan N, Naghshzan A, Peiravian F, Cheriki S, Nobahkti MJ. Hidden pulmonary arteries in tetralogy of Fallot and pulmonary artery pressure in patients operated with a pulmonary artery. BMC Cardiovascular Disorder. 2021;21(1):56. https://doi.org/10.1186/s12872-021-01877-y.
Ruth YE, Isra I, Abinash P, Swetha G, Endurance OE. Tetralogy of Fallot with absent left pulmonary artery in a patient who passed critical congenital heart disease screening. Cureus. 2022;14(10):e30604. https://doi.org/10.7759/cureus.30604.
Ho A, Salmon TP, Hayes N. A case series of three patients with unilateral disconnected pulmonary artery supplied by an ipsilateral patent ductus arteriosus: neonatal ductal stenting as palliation to preserve pulmonary arterial patency. Eur Heart J Case Rep. 2020;4(6):1-7. https://doi.org/10.1093/ehjcr/ytaa422.
Elder JC, Brofman BL, Kohn PM, Charms BL. Unilateral pulmonary artery absence or hypoplasia; radiographic and cardiopulmonary studies in five patients. Circulation. 1958;17(4 Part 1):557-66. https://doi.org/10.1161/01.cir.17.4.557.
Pfefferkorn JR, Loser H, Pech G, Toussaint R, Hilgenberg F. Absent pulmonary artery. A hint to its embryogenesis. Pediatr Cardiol. 1982;3(4):283-6. https://doi.org/10.1007/BF02427028.
Jiang Q, Zhang W, Hu R, Zhu Y, Hu J, Gu M, Zhang H. Outcomes of surgical reimplantation for anomalous origin of one pulmonary artery from the aorta. Ann Thorac Surg. 2021;111(4):1351-7. https://doi.org/10.1016/j.athoracsur.2020.07.023
Li W, Ma L, Xia Sh, Zou M, Chen W, Chen X. Early single-stage surgical revascularization of pulmonary artery in unilateral absence of a pulmonary artery. J Cardiothoracic Surg. 2021;16(80). https://doi.org/10.1186/s13019-021-01481-3.
Stumm M, Biermann D, Reichenspurner H, Gottschalk U, Müller G, Kozlik-Feldmann R, Riso A, Sachweh G. Autologous Tissue Technique to Repair Unilateral Isolated Absence of a Pulmonary Artery. World J Pediatric and Congenital Heart Surgery. 2021;12(4):547-59. https://doi.org/10.1177/2150135119825588.
Bentham JR, Zava NK, Harrison WJ, Shauq A, Kalantre A, Derrick G, Chen RH, Dhillon R, Taliotis D, Kang SL, Crossland D, Adesokan A, Hermuzi A, Kudumula V, Yong S, Noonan P, Hayes N, Stumper O, Thomson JDR. Duct stenting versus modified Blalock Taussig shunt in neonates with duct-dependent pulmonary blood flow: associations with clinical outcomes in a multicenter national study. Circulation. 2018;137(6):581-8. https://doi.org/10.1161/CIRCULATIONAHA.117.028972.
Glatz AC, Petit CJ, Goldstein BH, Kelleman MS, McCracken CE, McDonnell A. Comparison between patent ductus arteriosus stent and modified blalock-taussig shunt as palliation for infants with ductal-dependent pulmonary blood flow: insights from the congenital catheterization research collaborative. Circulation. 2018;137(6):589-601. https://doi.org/10.1161/CIRCULATIONAHA.117.029987.
Bahaidarah S, Al-Ata J, Alkhushi N, Azhar A, Zaher Z, Alnahdi B, Abdelsalam M, Elakaby A, Dohain A, Abdelmohsen G. Outcome of ductus arteriosus stenting including vertical tubular and convoluted tortuous ducts with emphasis on technical considerations. Egypt Heart J. 2021;73(1):83. https://doi.org/10.1186/s43044-021-00210-4.